Re inventing drug development jeffrey s handen 9781466579989 books amazonca skip to main content try prime en hello sign in account lists sign in account lists orders try prime cart books go search best sellers gift ideas new releases deals store . Re inventing drug development ebook handen jeffrey s amazonca kindle store skip to main contentca hello select your address kindle store hello sign in account lists account returns orders cart all gift cards best sellers prime gift ideas . However with many forces now conspiring to increase pressures on the commoditization of drug development industry support for truly novel often high risk development has eroded this calls for a drastic redefinition of what innovation is. Drug development investments have a painfully long time horizon food and drug administration fda approval for a single drug is estimated to take 10 to 15 years from start to finish and to cost upwards of 28 billion one reason for such high costs is the significant risk of failure the risks attribute to the unattractive 08 return on capital investment in drug development